UPDATE on 4/15/2022: After finishing my run as a GM on this, I can safely say that unless the rules for Spread were misunderstood by myself and one of my players, shotguns are completely broken and your players who pick that and Gun Nut will wipe things out within minutes. Even when increasing the difficulty of enemies, my players had no time at all killing things. The game is not balanced very well in many ways and there definitely needed to be simplification. It does many things well, but it does many things poorly and I don't think I'll be playing it or running it again in the future. Everything else still stands below,

So having began a first session as a GM with it this past Sunday in a custom homebrew setting of New Orleans, and also as a first time GM, it's a hell of a game to try and run and for everyone to learn on the first go. However, everyone had a lot of fun and after working some of the kinks out, it's a lot of fun to run, too! I do have some quibbles with the book itself that keep it from being a full 5.

1. No published errata means that both the PDF and hard copy are full of errors (Glowing One's base stats for health are incorrect, as an example) and also some rules are seemingly made more obtuse than they need to be (NPCs have Wealth 1, Wealth 2 -- but there's one paragraph in the NPC section that mentions what wealth is and it's basically you roll a d20 equal to the value next to Wealth. Well, why not say that up front?)

2. When it comes to looting, there is no table within the book itself that gives you what sample values there should be for a generic type of location. An example is given for it but no where in the book is it listed. Instead, it has to be found in the GM Guide they sell, which is incredibly stupid and forces you to buy another product. Luckily, one of my players found a table online made in Google Sheets that lists these values and automatically calculates the dice rolls (and it came from Modiphius' own forums no less).

3. I do not like the emphasis it places on Fallout 4. While a great game and great frame of reference, the Fallout universe is wide and expansive with multiple locations that could have been mentioned to detail the lore of the world. As is, all you get is the Commonwealth. What about the NCR, Vault 13, New Vegas, the Capital Wasteland, Appalachia? Just including anything more would have added so much more to it.

However, I will say that the constant exchange of AP is very fun and has made for many great scenarios already. I have a guy playing a Luck based character, a Ghoul fisherman focused around strength, a slick-talking mercenary, and a stealthy ex-Raider turned town bodyguard and everything meshes really well. What worries me is that the Dune core book came out in 2020 and errata wasn't made for that officially until January 2022, so if there is anything for this game, I'm afraid it might be long off.